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. 2010 Nov;12(6):797–807. doi: 10.2353/jmoldx.2010.090199

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© 2010 American Society for Investigative Pathology and the Association for Molecular Pathology. Published by Elsevier Inc. All rights reserved.

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Detection of sex chromosomes/autosomes ratio in CVS of 45,X pregnancies after methylation-sensitive restriction digestion. Real-time PCR after methylation-sensitive restriction digestion. Same samples and calculations as in Figure 4, except that the Turner (45,X) T5 sample was omitted. (P = 0.0162 for T1, P = 0.0265 for T2, P = 0.0162 for T3, and P = 0.0265 for T4). Gray and white dotted bars ( vs ) indicate, respectively, the average fold changes for euploid and Turner samples (the two groups are significantly different with P = 0.0003).

Inline graphic — Detection of sex chromosomes/autosomes ratio in CVS of 45,X pregnancies after methylation-sensitive restriction digestion. Real-time PCR after methylation-sensitive restriction digestion. Same samples and calculations as in Figure 4, except that the Turner (45,X) T5 sample was omitted. (P = 0.0162 for T1, P = 0.0265 for T2, P = 0.0162 for T3, and P = 0.0265 for T4). Gray and white dotted bars ( vs ) indicate, respectively, the average fold changes for euploid and Turner samples (the two groups are significantly different with P = 0.0003).