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A 72-year-old woman presented with a lipoma of the left hypothenar eminence. The patient complained of swelling and tenderness over the ulnar aspect of the hand with numbness and tingling in the left ring and little fingers. Intraoperatively, the tumor was found to extend into Guyon's canal and could be traced to originate from the bifurcation of the motor and sensory branches of the ulnar nerve. Two months after resection, the patient was symptom-free with full use of the hand.
