TABLE 1.

Representative study of effect of prednisolone on renal handling of sodium in a hydropenic rat with divided urine collections from left (L) and right (R) kidneys

Time, min	Body Wt 260 g
	V, μl/min		CIn, μl/min		UNaV, μEq/min		CNa/CIn × 100		Uosm, mOsm/kg H2O		Cosm, μl/min		${\text{T}}_{{\text{H}}_2\text{O}}^{\text{c}}/{\text{C}}_{\text{In}}\times 100$
	L	R	L	R	L	R	L	R	L	R	L	R	L	R
0	Prime with inulin 5 mg/100 g body wt and aqueous vasopressin 2.2 mU/100 g body wt and continue sustaining infusion delivering inulin 10 mg/100 g per hr and vasopressin 2.4 mμ/100 g per hr in normal saline given at rate of 1.5 ml/100 g per hr
0–300	Equilibration period
300–330	10.0	10.0	667	667	0.32	0.27	0.33	0.27	1,360	990	46.5	30.3	5.7	3.1
330–360	10.0	10.0	633	600	0.26	0.21	0.29	0.24	1,325	825	46.0	25.9	5.7	2.7
	Begin infusion of prednisolone 0.25 mg/100 g per hr into left renal artery
360–390	15.0	10.0	633	633	1.62	0.27	1.80	0.28	1,200	890	56.0	28.0	6.7	2.8
390–420	21.7	11.7	633	667	5.10	1.36	5.50	1.40	1,010	1,055	70.0	39.3	7.6	4.1
	Discontinue prednisolone infusion
420–450	25.0	13.3	596	596	3.88	1.54	4.48	1.78	1,050	850	81.0	37.0	8.9	4.0
450–480	15.0	10.0	561	571	4.42	0.88	5.41	2.50	1,200	1,155	59.0	38.4	7.8	3.2