TABLE 5.

Averages of serum (S) and urine values for control and prednisolone periods in six hydropenic rats (R) and six rats with diabetes insipidus (RD)

	Control		Prednisolone		Control		Control		Prednisolone		Control		Control		Prednisolone		Control
	L	R	L	R	L	R	L	R	L	R	L	R	L	R	L	R	L	R
	A) Six hydropenic rats
	R1						R3						R5
SNa, mEq/liter	143		144		144		145		140		145		144		144		145
V, μl/min	10.0	10.0	18.3	10.8	20.0	11.7	6.7	8.3	16.7	10.8	14.2	10.0	11.7	8.3	19.2	10.2	16.7	10.0
UNaV, μEq/min	0.29	0.24	3.36	0.81	4.15	1.21	0.19	0.23	3.17	2.15	1.34	0.77	0.17	0.11	1.48	0.15	0.13	0.15
Uosm, mOsm/kg H2O	1,340	910	1,105	972	1,125	1,002	1,188	1,100	907	1,180	1,157	1,440	430	415	450	380	465	380
Cosm, μl/min	46.0	28.2	63.0	33.2	70.0	37.7	26.5	30.5	47.5	38.2	51.4	46.0	16.1	11.0	25.8	12.4	24.5	12.0
CIn, μl/min	650	632	633	632	578	581	656	770	800	800	797	856	403	535	390	426	354	388
	R2						R4						R6
SNa, mEq/liter	140		141		140		135		136		136		140		142		143
V, μl/min	9.2	8.3	19.2	10.8	14.2	9.1	10.0	8.3	18.3	10.8	15.0	10.8	7.5	6.5	28.2	7.4	16.5	8.1
UNaV, μEq/min	0.30	0.15	0.53	0.14	0.55	0.28	0.23	0.17	1.01	0.26	0.63	0.13	0.26	0.17	1.91	0.72	1.36	0.51
Uosm, mOsm/kg H2O	903	765	726	780	730	968	507	572	500	524	500	599	1,345	1,299	881	1,850	1,190	1,820
Cosm, μl/min	26.1	20.5	44.5	26.8	31.3	28.3	17.0	17.2	30.2	19.0	24.1	21.6	32.4	26.0	75.4	43.2	55.0	42.7
CIn, μl/min	568	603	503	466	430	455	511	581	497	494	514	580	749	810	744	800	736	823
	B) Six rats with diabetes insipidus
	RD1						RD3						RD5
SNa, mEq/liter	140		141		140		139		139		140		130		133		133
V, μl/min	43.0	53.3	62.3	58.2	73.5	63.5	47.5	43.0	93.5	45.0	47.5	47.0	60.0	55.0	77.3	64.0	52.5	47.5
UNaV, μEq/min	0.23	0.15	0.67	0.36	0.50	0.63	0.59	1.19	1.03	0.82	0.22	0.37	0.60	0.96	1.17	0.96	0.67	0.71
Uosm, mOsm/kg H2O	62	76	89	77	100	90	81	66	91	79	61	105	45	63	59	53	43	62
Cosm, μl/min	11.1	16.9	26.6	18.5	32.5	25.1	14.0	10.5	21.0	13.0	11.0	18.5	9.5	12.2	17.0	13.0	8.5	11.0
CIn, μl/min	725	723	710	735	705	725	533	581	541	547	532	541	1,365	1,455	1,440	1,403	1,369	1,490
	RD2						RD4						RD6
SNa, mEq/liter	126		123		123		128		126		126		130		128		127
V, μl/min	70.0	60.0	98.3	69.0	73.5	52.5	47	52.5	66.0	57.3	55.5	50.0	42.5	52.5	58.3	56.6	50.0	55.0
UNaV, μEq/min	0.41	0.67	0.85	0.59	0.47	0.50	0.48	0.79	1.09	0.69	0.47	0.71	0.16	0.26	0.30	0.28	0.25	0.28
Uosm, mOsm/kg H2O	62	88	85	90	50	71	65	118	95	130	76	51	95	118	114	130	86	127
Cosm, μl/min	17.0	20.5	32.0	23.3	13.2	14.0	11.0	23.0	24.5	29.0	15.5	9.5	14.5	23.0	25.0	27.0	16.2	26.5
CIn, μl/min	1,230	1,320	1,231	1,172	1,458	1,265	882	940	924	908	920	922	583	625	608	594	537	584