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. Author manuscript; available in PMC: 2011 Oct 28.
Published in final edited form as: J Med Chem. 2010 Oct 28;53(20):7414–7427. doi: 10.1021/jm100884b

Table 5.

Aqueous solubility of ABI compound and its SMART counterpart as well as CA-4 and paclitaxel

Compound name Structure Media Solubility (μg/mL) Std Dev %CV
SMART-1 graphic file with name nihms242385t6.jpg Buffer pH 7.0 0.909 0.057 6.2
Water 0.833 0.169 20.3
ABI-5ga graphic file with name nihms242385t7.jpg Buffer pH 7.0 48.9 5.59 11.4
Water 11.3 1.70 15.0
Combretastatin A4 graphic file with name nihms242385t8.jpg Buffer pH 7.0 1.04 0.147 14.2
Water 2.83 0.330 11.7
Paclitaxel graphic file with name nihms242385t9.jpg Buffer pH 7.0 0.137 0.024 17.5
Water 0.021 0.004 20.7