Fig. 4.
Arousal response to stimuli during sleep. (A) (Left) During REM sleep, Gscl−/− mice (n = 4) tended to be awakened in response to acoustic stimuli, but Gscl+/+ mice (n = 5) remained asleep (χ2 test; P < 0.001). (Right) There was no significant difference between Gscl−/− mice and Gscl+/+ mice in the arousal response to an approaching object during NREM sleep (P = 0.2). Numbers in the table denote the number of stimulus trials. (B) The latency of Gscl−/− mice (n = 4) in response to an approaching object during REM sleep was shorter than that of Gscl+/+ mice (n = 5) (Mann–Whitney's u test, P < 0.001). Circles represent individual trials.