Fig. 5.
REM sleep rebound after REM sleep deprivation. (A) After 6 h of REM sleep deprivation (RSD) from ZT6–12, the time spent in REM sleep is displayed for each 3-h period during the recovery phase from ZT12–24. Both Gscl+/+ mice (n = 5) and Gscl−/− mice (n = 4) spent increased time in REM sleep from ZT12–15 compared with baseline. Gscl−/− mice exhibited a shorter REM sleep time than Gscl+/+ mice during ZT12–15, ZT15–18, and ZT21–24. (B) The time spent in NREM sleep after 6 h of RSD for each 3-h period from ZT 12–24. RSD did not alter NREM time in either Gscl+/+ or Gscl−/− mice. Data (mean ± SEM) were analyzed with ANOVA followed by the Tukey post hoc test. *P < 0.05.