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. 2010 Oct 4;107(42):18208–18213. doi: 10.1073/pnas.1012104107

Fig. 1.

Fig. 1.

Characterization of apnea in Mecp2−/+ mice studied in situ. (A) Representative traces show increased post-I activity in cVN that terminates before end of PN apnea and marked increase in HN that persists throughout PN apnea. (B) Example of tonic HN accompanied by tonic AbN during PN apnea. Note expiratory activity in one HN burst before the apnea (arrowed) and in several after PN apnea. (C) Incidence of apneas in Mecp2+/+ (n = 16) and Mecp2−/+ (n = 17) mice studied in situ. *P ≤ 0.0001 (unpaired t test). (D) Cycle triggered average of 20 consecutive cycles for integrated HN activity superimposed on integrated PN activity recorded in situ. There is significant HN activity during postinspiration.