Table 9.

Microchimerism in 13 patients according to HLA-allele detection with immunocytochemical (ICC) phenotyping and PCR^a

OT no.	Date of transplantation (mo/day/yr)b	Age of patient at transplantation (yr)	Tissue distribution
			Liver allograft		Blood	Lymph node		Skin
			ICC	PCR	PCR	ICC	PCR	ICC	PCR
Receiving treatment
42	3/23/71	16	NT	+	+	NT	+	NT	+
46	7/31/71	3	+++	+	+	+	+	+	+
77c	2/03/74	16	NT	+	NT	NT	+	NT	NT
133	7/26/77	44	NT	+	−	NT	+	−	+
144	4/17/78	39	+++	+	+	+	+	−	+
146	6/14/78	49	NT	+	+	NT	+	NT	−
175	4/13/80	41	NT	+	+	NT	+	NT	+
189	5/09/81	2	+++	+	+	+	+	+	+
194	7/12/81	26	+++	+	−	−	+	+	+
Not receiving treatment
73	10/08/73	4	+++	+	−	+	+	−	+
92	11/27/74	11	+++	+	−	+	+	−	+
150	7/15/78	15	NT	+	+	+	+	−	−
169	12/03/79	21	+++	+	−	+	+	+	+

NT = not tested.

^aThese patients were in addition to the nine studied with Y-chromosome detection (Table 8).

^bAll postoperative studies in April to July 1992.

^cSkin and blood not taken at autopsy. However, all other tissues tested positive with PCR for donor DNA (see Fig. 18).