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. Author manuscript; available in PMC: 2010 Oct 26.
Published in final edited form as: Cancer Prev Res (Phila). 2009 Jul;2(7):617–624. doi: 10.1158/1940-6207.CAPR-09-0025

Table 3.

The Cumulative Effects of Unfavorable Genotypes on SPT/Recurrence

Number of unfavorable genotypes * SPT/Recurrence N (%) No SPT/Recurrence N (%) HR (95% CI) ** P value
Reference group ≤4 18(10.91) 147(89.09) 1 Reference
5~6 62(37.58) 103(62.42) 4.29(2.52–7.29) 7.59×10−8
7 34(61.82) 21(38.18) 9.16(5.52–17.83) 1.80×10−14
≥8 25(96.15) 1(3.85) 26.72(14.00–50.99) <1.00×10−20
P for trend <1.00×10−20
*

Unfavorable genotype was based on the 12 chromosomal SNPs and one mitochondrial SNP as described in text.

**

Adjusted for age, gender, smoking status, ethnicity, tumor site, tumor stage, and treatment.