Table 2. Group differences in brain volume measures.
Caucasian (Nā=ā44) | African-American (Nā=ā25) | F value | p value | |
Total Cerebrum | 1178.3 (115.0) | 1076.0 (67.9) | 17.92 | <0.0001 |
GM+WM/CSF Ratio | 667.3 (81.8) | 629.8 (54.8) | 13.77 | 0.0004 |
Lateral Ventricles | 21.6 (10.9) | 15.2 (5.0) | 0.04 | 0.8503 |
0.018 (0.009) | 0.014 (0.004) | 1.30 | 0.2585 | |
Total Gray Matter | 665.2 (81.7) | 627.2 (54.5) | 3.13 | 0.0816 |
0.566 (0.061) | 0.583 (0.048) | 0.52 | 0.4752 | |
Total White Matter | 444.7 (79.5) | 429.6 (62.1) | 2.19 | 0.1438 |
0.377 (0.054) | 0.398 (0.044) | 1.79 | 0.1856 | |
Amygdala, L | 2.4 (0.5) | 2.2 (0.5) | 1.31 | 0.2568 |
0.0021 (0.0004) | 0.0021 (0.0003) | 3.65 | 0.0607 | |
Amygdala, R | 2.4 (0.4) | 2.2 (0.4) | 1.96 | 0.1668 |
0.0020 (0.0004) | 0.0021 (0.0004) | 6.05 | 0.0167 | |
Caudate, L | 4.0 (0.7) | 3.8 (0.5) | 1.93 | 0.1700 |
0.0034 (0.0006) | 0.0036 (0.0005) | 0.19 | 0.6676 | |
Caudate, R | 4.4 (0.7) | 4.1 (0.6) | 2.64 | 0.1092 |
0.0037 (0.0006) | 0.0040 (0.0005) | 0.51 | 0.4771 | |
Hippocampus, L | 3.6 (0.5) | 3.5 (0.5) | 1.34 | 0.2513 |
0.0031 (0.0005) | 0.0032 (0.0004) | 0.00 | 0.9510 | |
Hippocampus, R | 3.5 (0.5) | 3.5 (0.5) | 0.01 | 0.9245 |
0.0030 (0.0005) | 0.0033 (0.0005) | 1.31 | 0.2561 | |
Orbitofrontal Cortex, L | 6.8 (1.9) | 7.8 (1.7) | 7.50 | 0.0080 |
0.0057 (0.0014) | 0.0072 (0.0016) | 10.79 | 0.0017 | |
Orbitofrontal Cortex, R | 7.6 (1.6) | 8.3 (1.7) | 3.38 | 0.0708 |
0.0065 (0.001) | 0.0077 (0.002) | 7.10 | 0.0098 |
The top measure for each region is the mean volume (mLs) and the bottom measure is the ratio of regional volume/cerebrum (defined as GM+WM+CSF). Standard deviation is in parentheses. Each variable has 1 df, with 68 df for each model.