Table 3. Age-matched group differences in brain volume measures.
Caucasian (Nā=ā31) | African-American (Nā=ā25) | F value | p value | |
Total Cerebrum | 1173.4 (119.4) | 1076.0 (67.9) | 16.60 | 0.0002 |
GM+WM/CSF Ratio | 680.9 (89.5) | 629.8 (54.8) | 12.86 | 0.0008 |
Lateral Ventricles | 20.1 (11.26) | 15.2 (5.0) | 0.02 | 0.8782 |
0.017 (0.009) | 0.014 (0.004) | 1.07 | 0.3064 | |
Total Gray Matter | 678.6 (89.5) | 627.2 (54.5) | 2.92 | 0.0938 |
0.580 (0.063) | 0.584 (0.048) | 0.48 | 0.4925 | |
Total White Matter | 450.7 (68.0) | 429.6 (62.1) | 2.19 | 0.1453 |
0.385 (0.048) | 0.398 (0.044) | 1.71 | 0.1965 | |
Amygdala, L | 2.3 (0.5) | 2.2 (0.5) | 2.32 | 0.1341 |
0.0019 (0.0004) | 0.0021 (0.0004) | 4.47 | 0.0396 | |
Amygdala, R | 2.3 (0.5) | 2.2 (0.4) | 1.76 | 0.1912 |
0.0019 (0.0004) | 0.0021 (0.0004) | 5.50 | 0.0231 | |
Caudate, L | 4.1 (0.7) | 3.8 (0.5) | 1.94 | 0.1701 |
0.0035 (0.0006) | 0.0036 (0.0005) | 0.03 | 0.8670 | |
Caudate, R | 4.4 (0.7) | 4.1 (0.6) | 2.34 | 0.1324 |
0.0038 (0.0006) | 0.0039 (0.0005) | 0.29 | 0.5947 | |
Hippocampus, L | 3.7 (0.5) | 3.5 (0.5) | 0.64 | 0.4266 |
0.0032 (0.0005) | 0.0032 (0.0004) | 0.01 | 0.9142 | |
Hippocampus, R | 3.6 (0.6) | 3.5 (0.5) | 0.01 | 0.9118 |
0.0031 (0.0005) | 0.0033 (0.0005) | 1.23 | 0.2734 | |
Orbitofrontal Cortex, L | 7.0 (2.2) | 7.8 (1.7) | 6.06 | 0.0174 |
0.0059 (0.0016) | 0.0072 (0.0016) | 7.85 | 0.0072 | |
Orbitofrontal Cortex, R | 7.9 (1.6) | 8.3 (1.7) | 2.74 | 0.1040 |
0.0068 (0.0013) | 0.0077 (0.0016) | 5.61 | 0.0216 |
The top measure for each region is the mean volume (mLs) and the bottom measure is the ratio of regional volume/cerebrum (defined as GM+WM+CSF). Standard deviation is in parentheses. Each variable has 1 df, with 55 df for each model.