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. 2010 Oct 26;5(10):e13632. doi: 10.1371/journal.pone.0013632

Figure 8. Testicular response to hCG exposure in SMARKO mice.

Figure 8

A. Testis weight increased significantly in SMAR control, but not in SMARKO 16 hours after hCG treatment, presumably reflecting alterations in interstitial fluid volume. B. Serum testosterone concentrations increased significantly in both SMARKO and control adult males after exposure to hCG, but this increase was larger in controls than in KOs. C. Interstitial fluid testosterone concentrations were significantly higher in control testes than in SMARKOs at d100 after exposure to hCG. D. Average blood flow (Pfu) through adult SMARKO and control testes 16 hours after exposure to hCG. E. Average vasomotion frequency in adult SMARKO and control testes 16 hours after exposure to hCG. F. Average vasomotion amplitude in adult SMARKO and control testes 16 hours after exposure to hCG. Note that vasomotion frequency and amplitude were only measured in the two hcg-treated controls testes in which vasomotion could still be detected. Values are mean ± SEM (n = 5–7 mice), * p<0.05, ** p<0.01, *** p<0.001, compared to control littermates. a p<0.01, compared to untreated mice.