Table 2.
Sialogogues.
Gustatory and tactile sialogogues* | Pharmacological sialogogues |
---|---|
Acid-tasting substances | Anetholetrithione |
acidic (sugar-free) sweets | Benzapyrone |
acidic or effervescent drinks (lemon juice, citric acid, buttermilk) | Betanechol chloride |
Carbachol | |
citric acid crystals | Cevimeline** |
cotton-wool gauze soaked in a citric acid and glycerine solution | Folia Jaborandi and tinctura Jaborandi |
Neostigmine, neostigmine bromide, pyridostigmine bromide, destigmine bromide | |
lemon pastilles | |
lemon slices | Nicotinamide and nicotine acid |
vitamin C tablets | Pilocarpine hydrochloride**, pilocarpine nitrate |
Miscellaneous substances: | Potassium iodide |
dried pieces of reed root (calami rhizome) | Trithioparamethoxyphenylpropene |
sugar-free chewing gum | |
sugar-free sweets | |
vegetables or fruits |
Not all substances are recommended in dentulous patients as acidic products may induce demineralization of dental hard tissues
Only these agents have been approved for relief of xerostomia in humans and have undergone substantial, controlled clinical testing