Table 1.

Relevant Assay Details for Each Biomarker.

Biomarker	Sensitivity	Standard Range	Inter-Assay Variability (%)	Intra-Assay Variability (%)	Reference* Range
CRP (mg/L)	0.1	0–250	6.7	3.5	1.4 – 11.0
IL-6 (pg/mL)	0.1	0–10	9.8	3.0	3.12 – 12.5
IL-6sR (pg/mL)	6.5	31.2 – 2000	12.6	2.4	17,000 – 46,000
IL-1sRII (pg/mL)	<10	31.2 – 2000	14.8	5.5	6000 – 18000
sTNFRI (pg/mL)	<3.0	7.8 – 500	11.7	3.0	484 – 1407
sTNFRII (pg/mL)	0.6	7.8 – 500	8.4	5.3	829 – 2262
IL-8 (pg/mL)	0.03	1.6 – 5000	12.1	4.2	1.75 – 7.74
IL-15 (pg/mL)	0.11	1.03 – 750	10.9	5.1	0.98 – 3.23
Adiponectin (μg/ml)	0.25	3.9 – 250	13.9	7.1	1.20 – 19.97
IL-1ra (pg/mL)	6.26	31.2 – 2000	10.4	2.6	105 – 1062
IL-2sRα (pg/mL)	< 10	78 – 5000	9.6	2.7	410 – 2623
TNF-α (pg/mL)	0.11	0.5 – 32	15.6	5.2	0 – 2.14

All visits from one sample were run on the same plate.

^*Values obtained from manufacturer kit insert, n<100 per biomarker.