. Author manuscript; available in PMC: 2011 Sep 1.

Published in final edited form as: J Affect Disord. 2010 Mar 12;125(1-3):241–248. doi: 10.1016/j.jad.2010.02.112

Table 4.

Association of depressive and anxiety disorder characteristics with coronary heart disease

	No CHD N=1673	CHD N=97

	% or mean (SD)	% or mean (SD)	OR	95% CI	p
	Unadjusted		Adjusted^a
Type of depressive disorder^b
First onset major depressive disorder (vs. recurrent)	46.4	41.8	0.95	0.56–1.61	.85
Atypical symptoms	20.8	24.2	1.53	0.83–2.83	.17
Melancholic symptoms	11.9	16.7	1.08	0.53–2.18	.84
Late onset (≥ 30 years old)	35.0	61.8	1.11	0.65–1.92	.70
Type of anxiety disorder^c
Generalized anxiety disorder	44.9	50.0	1.15	0.72–1.82	.56
Social phobia	55.5	53.6	1.08	0.68–1.72	.74
Panic disorder	55.1	53.6	1.13	0.71–1.80	.62
Agoraphobia	16.0	25.0	1.21	0.70–2.10	.49
Late onset (≥ 30 years old)	22.6	43.4	1.06	0.65–1.73	.83
Duration^d
Percent of time with symptoms in past 4 years	52.4 (35.6)	58.8 (35.3)	1.02	0.56–1.86	.95
Severity^d
Current depressive symptoms score (IDS)	28.5 (12.4)	32.2 (13.0)	1.32^e	1.05–1.65	.02
Current anxiety symptoms score (BAI)	16.5 (10.8)	20.0 (9.7)	1.36^e	1.11–1.66	.003
Psychoactive medication^d
Selective serotonin reuptake inhibitor use	25.1	21.6	0.87	0.52–1.45	.60
Tricyclic antidepressant use	3.8	7.2	1.56	0.68–3.57	.30
Other antidepressant use	8.8	12.4	1.26	0.65–2.41	.49
Benzodiazepine use	10.5	22.7	1.60	0.95–2.71	.08

Based on logistic regression analyses adjusted for age, sex, and education; each line represents a single analysis.

Within sub-sample of persons with a current (past year) depressive disorder: N=1266; first onset vs. recurrent: persons with dysthymia only (N=44) were excluded.

Within sub-sample of persons with a current (past year) anxiety disorder: N=1352.

Within sub-sample of persons with a current (past year) depressive and/or anxiety disorder: N=1770.

Per SD increase: IDS: SD=12.9; BAI: SD=10.7.