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. 2010 Oct 25;207(11):2383–2393. doi: 10.1084/jem.20101335

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© 2010 Li et al.

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Figure 2. — Electron density maps for the microbial glycolipids. (A–D) Representation of the final 2F_o-F_c maps drawn around glycolipids GalA-GSL (A and C) and BbGL-2c (B and D) from the ternary mCD1d–glycolipid–TCR complexes. The maps are contoured at 1 σ and shown as a blue mesh in side view (A and B) and looking down into the binding groove from the top (C and D). Hydrophobic mCD1d residues interacting with the lipid backbone and charged residues contacting the polar moieties of the glycolipid sugar are depicted. The α2 helix is removed for clarity in A and B. Relative positions of TCR CDR1-α, CDR3-α, and CDR3-β are depicted for general orientation in A and B.