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. 2010 Oct 25;207(11):2395–2405. doi: 10.1084/jem.20100995

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© 2010 Abboud et al.

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Figure 4. — IgG1 and IgG2a mAbs protect wild-type but not FcRγ^−/−/RIIB^−/− or FcRγ^−/− mice from B. anthracis infection. (A) Kaplan-Meier analysis of survival rate of FcRγ^−/−/RIIB^−/− or wild-type mice treated with IgG1 and IgG2a mAbs or isotype control antibodies (n = 10). (B) Kaplan-Meier analysis of survival rate of FcRγ^−/− or wild-type mice treated with IgG1 and IgG2a mAbs or isotype control antibodies (n = 10). The log-rank test was used to determine significance between wild-type and FcRγ^−/−/RIIB^−/− and FcRγ^−/− mouse groups treated with IgG1 and IgG2a mAbs. Data shown are representative of two independent experiments.