Table 1.
Protective effects of Tinospora cordifolia on some hepatic biochemical parameters in lead-exposed mice
| Groups | SOD | CAT | AST | ALT | ALP | ACP | Hepatic lead |
|---|---|---|---|---|---|---|---|
| Control (untreated animals) | 6.25±0.14 | 161±0.84 | 2.28±0.04 | 3.14±0.06 | 15.1±0.24 | 1.73±0.08 | 0.07±0.07 |
| Pb | 2.27±0.16a | 117±2.22a | 5.67±0.19a | 7.80±0.15a | 18.1±0.54a | 5.61±0.07a | 2.14±0.17a |
| TC (stem) | 6.84±0.33 | 183±2.22a | 3.62±0.11 | 3.21±0.08 | 15.3±0.12a | 3.14±0.06 | 0.17±0.03 |
| TC (leaf) | 5.61±0.07 | 148±3.35 | 3.72±0.22 | 3.62±0.11 | 15.9±0.68 | 2.52±0.04 | 0.21±0.01 |
| TC (stem)+Pb | 4.83±0.06b | 161±4.99b | 3.11±0.59b | 4.67±0.05b | 13.2±0.33b | 2.46±0.01b | 1.14±0.18b |
| TC (leaf)+ Pb | 3.62±0.13 | 153±1.34b | 3.21±0.08b | 4.04±0.22b | 11.7±0.26b | 2.23±0.06b | 1.34±0.09b |
TC, Tinospora cordifolia; Pb, lead; SOD, superoxide dismutase (units/min/mg protein); CAT, catalase (μm H2O2 consumed/min/mg protein); AST, aspartate aminotransferase (per min per mg protein); ALT, alanine aminotransferase (per min per mg protein); ALP, alkaline phosphatase (one king Armstrong unit 1 UI-1); ACP, acid phosphatase (one king Armstrong unit/ 1 UI-1); lead liver concentration (μg/g); Values are mean±S.E, n = 6;
a
p< 0.05 compared to control (untreated) animals;
b
p< 0.05 compared to lead-exposed animals