Skip to main content
. Author manuscript; available in PMC: 2010 Oct 27.
Published in final edited form as: Curr Opin Lipidol. 2009 Jun;20(3):217–226. doi: 10.1097/MOL.0b013e32832b3f4c

Figure 4. Conservation of the putative IRE motif in the apob promoter.

Figure 4

The promoter sequences of rat, mouse, and human apob genes were aligned for the comparison of IRE, the DNA motif that is responsible for binding FoxO1 and mediating the inhibitory effect of insulin on target gene expression. The putative IRE motif along with its nucleotide positions is indicated. IRE, insulin-responsive element.