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Membrane topology of the hMT1 melatonin receptor showing amino acids conserved in the hMT2 receptor. Gray circles denote amino acids identical in the hMT1 and hMT2 melatonin receptors. The two glycosylation sites on the hMT1 receptor are denoted (Y) in the N terminus. [Adapted from Reppert SM and Weaver DR (1995) Melatonin madness. Cell 83:1059–1062. Copyright © 1995 Elsevier Inc. Used with permission.]
