TABLE 3.

Carboxyl-terminal protein binding partners for AMPA and kainate receptor subunits

Entries indicate data supporting direct interactions between the indicated protein and glutamate receptor subunit.

Protein	Class	GluA1	GluA2	GluA3	GluA4	GluK1	GluK2	GluK5
CASK	PDZ						Y2H,coIP,EP1
GRIP	PDZ		Y2H,coIP,IHC2,3,4,5	Y2H,coIP,IHC2,3,4,6	Y2H,coIP,IHC7	Y2H,coIP,EP8
GRIP2	PDZ		Y2H,coIP,IHC4,5,7	Y2H,coIP,IHC4,7	Y2H,coIP,IHC7		Y2H,coIP,EP8
mLIN-10	PDZ	coIP9	coIP9
PICK1	PDZ		Y2H,coIP,IHC2,6	Y2H,coIP,IHC2,6	Y2H,coIP,IHC2,6	Y2H,coIP,EP8	Y2H,coIP,EP8
PSD95	PDZ					Y2H,coIP,EP8	Y2H,coIP,IHC,EP8,10	coIP,IHC,EP10
SAP97	PDZ	coIP,IHC11,12					Y2H,coIP,EP10
SAP102	PDZ						Y2H,coIP,EP10
Shank3	PDZ	Y2H,coIP,IHC13
Syntenin	PDZ	Y2H14	Y2H14	Y2H14	Y2H14	Y2H,coIP,EP8	Y2H,coIP,EP8
RIL	PDZ / LIM	Y2H,coIP,IHC,EP15
4.1	Cytoskeletal	Y2H,coIP,IHC16,17			coIP,IHC18
α-Actinin-1	Cytoskeletal				Y2H,coIP,IHC19
Actinfilin	Cytoskeletal					Y2H,coIP,IHC20	Y2H,coIP,IHC20
Contactin	Cytoskeletal						coIP21
Dynamin-1	Cytoskeletal						coIP21
Dynamitin	Cytoskeletal						coIP21
Profilin	Scaffold						coIP21
Spectrin	Scaffold						coIP21
AP2	Adaptor		coIP,IHC,EP22,23
NSF	ATPase		Y2H,coIP,IHC,EP24,25,26				coIP21
IQGAP1	GTPase				Y2H,coIP,IHC19
Calmodulin	Ca2+ sensor						coIP21
VILIP1	Ca2+ sensor						coIP21
VILIP3	Ca2+ sensor						coIP21
14-3-3	Other27						coIP21	coIP28
COPI	Other27							coIP28
G-α(q/11)	Other27							coIP,EP29
SUMO	Other27						Y2H,coIP,IHC,EP30

coIP, coimmunoprecipitation or pull-down assay; EP, electrophysiology; IHC, immunohistochemistry; Y2H, yeast two-hybrid.

¹ Coussen et al. (2002).

² Dev et al. (1999).

³ Dong et al. (1997).

⁴ Wyszynski et al. (1999).

⁵ Dong et al. (1999).

⁶ Xia et al. (1999).

⁷ Srivastava et al. (1998).

⁸ Hirbec et al. (2003).

⁹ Stricker and Huganir (2003).

¹⁰ Garcia et al. (1998).

¹¹ Leonard et al. (1998).

¹² Sans et al. (2001).

¹³ Uchino et al. (2006).

¹⁴ Hirbec et al. (2002).

¹⁵ Schulz et al. (2004).

¹⁶ Hayashi et al. (2005).

¹⁷ Shen et al. (2000).

¹⁸ Coleman et al. (2003).

¹⁹ Nuriya et al. (2005).

²⁰ Salinas et al. (2006).

²¹ Coussen et al. (2005).

²² Kastning et al. (2007).

²³ Lee et al. (2002).

²⁴ Nishimune et al. (1998).

²⁵ Osten et al. (1998).

²⁶ Song et al. (1998).

²⁷ Synaptic transmembrane proteins, signaling proteins, ubiquitin-like proteins, or transport regulatory proteins.

²⁸ Vivithanaporn et al. (2006).

²⁹ Ruiz et al (2005).

³⁰ Martin et al. (2007).