Figure 7. In vivo PD-1 blockade enhances both non–SIV-specific and SIV-specific humoral immunity.

PD-1 blockade was performed in 5 SIV-infected animals at 10 weeks following infection. 2 SIV-infected animals treated with an isotype Ab served as controls. (A) Serum anti-FliC IgG Ab titers. (B) Serum anti-Gag p27 IgG Ab titers.