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. Author manuscript; available in PMC: 2010 Oct 27.
Published in final edited form as: Am J Respir Cell Mol Biol. 2002 Nov;27(5):568–574. doi: 10.1165/rcmb.4821

Figure 2.

Figure 2

Time course and dose response studies on AP-1 trans-activation by coals from PA (PSOC-1198; closed circles) and UT (PSOC-459; open circles). A total of 8 × 103 P+1-1 were seeded, cultured, and processed as described in the legend for Figure 1. (a) For the dose response study, cells were treated with different amounts of PSOC-1198 or PSOC-459. After being cultured for 36 h, the luciferase activity was measured. (b) For the time course study, cells were treated with the PSOC-1198 or PSOC-459 coals at 40 μg/cm2 and harvested at time points indicated for the luciferase activity assay. The results are presented as relative AP-1 activity. Each bar indicates the mean and standard deviation of four identically treated assay wells.