Figure 5. Rpn13 deficiency affects body weight and composition.

Body weights (A) and composition (B) were measured for the indicated mice at the time points and intervals shown. Minimum 3, maximum 38 mice were studied at each time point. Numbers above bars indicate P values compared to Wts. (C) Representative images of CAT-scan analysis of 16-weeks old male mice with the indicated genotype. An additional male and a female Rpn13 ^−/− mouse were also analyzed along with Wt littermates and showed similar increases in fat deposits as marked on the image.