Table 1. Phosphorylated Ncl interacts individually with Tpt1 and Oct4.
Variables | Pearson's correlation coefficient | % overlap of Ncl or Ncl-P | % overlap of Tpt1 or Oct4 |
Interphase Ncl/Tpt1 | 0.249±0.004 | 10.85±0.57 | 5.56±0.13 |
Mitotic Ncl-P/Tpt1 | 0.761±0.013 | 43.44±2.65 | 69.66±3.05 |
Interphase Ncl-P/Tpt1 | 0.524±0.008 | 38.73±1.51 | 18.64±5.06 |
Interphase Ncl-P/Oct4 | 0.815±0.005 | 65.62±2.59 | 33.00±1.87 |
Ncl only interacts with Tpt1 when phosphorylated and the Ncl-P/Tpt1 interaction is most prominent during mitosis. Ncl-P also shows interaction with Oct4 during interphase. Data are represented as mean ± SEM.