Table 1. A list of 19 genes that are differentially expressed in more than 4 cancer types and their relevance to different cancer types.
Gene ID | Direction of regulation | Reported to be related to cancers | |||||||||||||
Breast | Colon | Kidney | Lung | Pancreas | Prostate | Stomach | B. | C. | K. | L. | Pa. | Pr. | S. | Other cancer types | |
CDC2 | ↑ | ↑ | ↑ | ↑ | ↑ | * | * | * | * | * | liver cancer; squamous cell carcinoma;nasopharyngeal carcinoma | ||||
AURKA | ↑ | ↑ | ↑ | ↑ | ↑ | * | * | * | * | * | * | ovarian cancer;esophageal squamous cancer;uterine cancer;bladder cancer | |||
ABCA8 | ↓ | ↓ | ↓ | ↓ | ↓ | ||||||||||
DPT | ↓ | ↓ | ↓ | ↓ | ↓ | ||||||||||
TOP2A | ↑ | ↑ | ↑ | ↑ | ↑ | * | * | * | bladder cancer;ovarian cancer; squamous cell carcinoma | ||||||
MMP7 | ↑ | ↑ | ↑ | ↑ | * | * | * | * | * | ovarian cancer; oral cancer; rectal cancers; bladder cancer; liver cancer | |||||
MAD2L1 | ↑ | ↑ | ↑ | ↑ | * | * | thyroid carcinomas; oesophageal squamous cancer | ||||||||
KLF4 | ↓ | ↓ | ↓ | ↓ | * | * | * | esophageal cancer;bladder cancer | |||||||
MELK | ↑ | ↑ | ↑ | ↑ | * | brain cancer;endometrial cancer | |||||||||
C7 | ↓ | ↓ | ↓ | ↓ | * | * | uterine cervical cancers | ||||||||
ECT2 | ↑ | ↑ | ↑ | ↑ | * | ||||||||||
PRC1 | ↑ | ↑ | ↑ | ↑ | * | ||||||||||
RRM2 | ↑ | ↑ | ↑ | ↑ | * | * | * | ||||||||
ALDH1A1 | ↓ | ↓ | ↓ | ↓ | * | non-small cell bronchopulmonary cancer; liver cancer; T-cell leukemia | |||||||||
PMAIP1 | ↑ | ↑ | ↑ | ↑ | * | * | * | ||||||||
FABP4 | ↓ | ↓ | ↓ | ↓ | * | Bladder cancer; | |||||||||
COL11A1 | ↑ | ↑ | ↑ | ↑ | adenomas; | ||||||||||
TTK | ↑ | ↑ | ↑ | ↑ | |||||||||||
CENPF | ↑ | ↑ | ↑ | ↑ | * |
“↑” indicates up-regulated gene expression in the corresponding cancer type while “↓”is down-regulation. “*” indicates that a gene has been reported as relevant to the corresponding cancer type. “B.” for breast cancer; “C.” for colon cancer; “K.” for kidney cancer”; “L.” for lung cancer”; “Pa.” for pancreatic cancer”; “Pr.” for prostate cancer” and “S.” for stomach cancer”.