Table 4. Performance of various potentials on selecting models generated in CASP5-8 experiments as collected by Rykunov and Fiser [37].
Scoring function | models only | native included | ||
Averagea | ranked 1b | Averagec | ranked 1d | |
QMEAN6 | 2.87 | 85 | 1.71 | 113 |
RWplus | 2.97 | 57 | 1.78 | 106 |
RW | 3.08 | 51 | 1.71 | 110 |
QMEANall_atom | 3.59 | 74 | 1.71 | 119 |
QMEANSSE_agree | 3.74 | 62 | 3.72 | 39 |
QMEANACC_agree | 4.04 | 40 | 3.78 | 48 |
RF_CB_SRS_OD | 4.16 | 61 | 2.08 | 110 |
RF_CB_OD | 4.62 | 62 | 2 | 111 |
RF_HA_SRS | 4.65 | 49 | 1.38 | 137 |
RF_CB_SRS | 4.72 | 56 | 2.18 | 114 |
OPUS_CA | 4.72 | 79 | 5.13 | 55 |
VSCOREcombined | 4.79 | 53 | 2.2 | 117 |
QMEAN-pairwise | 4.8 | 54 | 3.15 | 85 |
Rosetta | 5.01 | 57 | 4.09 | 68 |
Dong-pair | 5.01 | 58 | 6.32 | 4 |
RF_CB | 5.06 | 52 | 2.46 | 106 |
VSCORE-pair | 5.08 | 54 | 1.85 | 128 |
PROSAcombined | 5.11 | 57 | 3.38 | 87 |
OPUS_PSP | 5.39 | 54 | 2.99 | 118 |
RF_HA | 5.44 | 62 | 2.78 | 112 |
DOPE | 5.77 | 54 | 3.27 | 95 |
dFIRE | 6.03 | 50 | 5.69 | 33 |
PROSA-pair | 6.03 | 56 | 3.54 | 95 |
QMEAN-torsion | 6.71 | 45 | 3.24 | 114 |
Shortle2006 | 6.85 | 35 | 1.79 | 129 |
Liang_geometric | 6.88 | 44 | 2.48 | 114 |
QMEANsolvation | 7.32 | 33 | 6.27 | 54 |
Shortle2005 | 7.73 | 42 | 3.39 | 109 |
Floudas-CM | 7.75 | 38 | 7.05 | 42 |
Floudas-Ca | 7.79 | 33 | 8.36 | 10 |
NAMD_1000 | 8.06 | 24 | 4.96 | 78 |
Melo-ANOLEA | 9.62 | 19 | 5.19 | 86 |
PC2CA | 9.75 | 19 | 5.06 | 85 |
Melo-NL | 9.99 | 14 | 5.85 | 80 |
NAMD_1 | 11.91 | 5 | 10.98 | 24 |
Randome | 9.72 | 13.9 | 10.1 | 8.3 |
The average rank of lowest energy decoy according to GDT_TS score (over 143 decoy sets) in the absence of native structures.
The number of sets when the best model was ranked as first, in the absence of native structures.
The average rank of the lowest energy decoy in GDT_TS when native structures are present.
The number of sets when the best model was ranked as first when native structures are present.
Expected random values were generated by picking a wining model fromthe decoy sets randomly. Average values over 1000 random trials are shown [37].