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. 2010 Oct 12;11:504. doi: 10.1186/1471-2105-11-504

Table 11.

Comparisons between the different methods on the Consolidated3.19 network

Method
MCL MCLO MCL-CAw CMC HACO

#Predicted 116 119 122 77 101
Wodak
(#145)
#Matched 70 80 82 67 57
Precision 0.603 0.672 0.672 0.870 0.564
#Derived 79 80 82 67 64
Recall 0.545 0.552 0.566 0.462 0.441

MIPS
(#157)
#Matched 48 65 68 56 40
Precision 0.414 0.546 0.557 0.727 0.396
#Derived 63 65 68 56 57
Recall 0.401 0.414 0.433 0.357 0.363

Aloy
(#76)
#Matched 54 56 57 45 44
Precision 0.466 0.471 0.467 0.584 0.436
#Derived 55 56 57 45 45
Recall 0.724 0.737 0.750 0.592 0.592

Methods considered: MCL, MCLO, MCL-CAw, CMC and HACO. CMC performed the best in terms of precision, while MCL-CAw performed the best in recall. #Matched: #Predictions matching some benchmark complex(es). #Derived: #Benchmark complexes derived by some predicted complex(es).

The Consolidated3.19 network

#Proteins 1622; #Interactions 9704