Table 19.
Complexes derived with lesser accuracy or missed by MCL-CAw due to affinity scoring
| Matched benchmark complex | #Proteins in complexes from | #Incorrect proteins in complexes from ICD(G+K) | Accuracies (Jaccard scores) | ||||
|---|---|---|---|---|---|---|---|
| Name | #Proteins | G+K | ICD(G+K) | Missed | Addnl | G+K | ICD(G+K) |
| Kornbergs SRB | 25 | 24 | 23 | 2 | 0 | 0.960 | 0.920 |
| SWI/SNF | 12 | 11 | 8 | 4 | 0 | 0.769 | 0.667 |
| TRAPP | 10 | 10 | 9 | 1 | 0 | 1.000 | 0.900 |
| 19/22 S reg | 22 | 20 | 27 | 0 | 5 | 0.909 | 0.815 |
| TRAMP | 3 | 4 | 7 | 0 | 4 | 0.750 | 0.429 |
| Alpha-1,6 | 5 | 9 | 11 | 0 | 6 | 0.556 | 0.455 |
| eIF3 | 7 | 8 | 14 | 1 | 8 | 0.500 | 0.400 |
| Protein phosp | 3 | 5 | 9 | 0 | 4 | 0.600 | 0.333 |
| Cdc73p/Paf1p | 7 | 7 | 18 | 0 | 11 | 0.556 | 0.388 |
| Chs5p/Arf-1 | 6 | 8 | 10 | 2 | 6 | 0.556 | 0.400 |
The upper half shows sample complexes from Wodak lab derived with lower accuracies from the ICD(Gavin+Krogan) network compared to those from the Gavin+Krogan network. The lower half shows those missed from the ICD(Gavin+Krogan) network. The #Incorrect proteins in ICD(Gavin+Krogan) network is with respect to the benchmark complexes.