Table 6.
Co-localization scores for predicted components from MCL and MCL-CAw
| Co-localization scores | |||
|---|---|---|---|
| PPI Network | MCL clusters | MCL-CAw cores | MCL-CAw complexes |
| Gavin+Krogan | 0.730 | 0.890 | 0.866 |
| ICD(Gavin+Krogan) | 0.830 | 0.936 | 0.912 |
| FSW(Gavin+Krogan) | 0.830 | 0.931 | 0.912 |
| Consolidated3.19 | 0.790 | 0.923 | 0.908 |
| Bootstrap0.094 | 0.788 | 0.895 | 0.874 |
Findings: (i) The complexes produced after CA-refinement showed higher scores than those of MCL; (ii) The complexes predicted from the scored networks showed higher scores than from the Gavin+Krogan network; (iii) The cores in MCL-CAw showed higher scores than whole complexes.