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. 2010 Oct 27;5(10):e15401. doi: 10.1371/journal.pone.0015401

Figure 3. Selective deficits in pattern completion during retrieving spatial reference memory in DAT+/− knockout mice.

Figure 3

(A). Both DAT+/− mice and control mice exhibited strong preference to the target quadrant where the platform was previously located under full cue conditions. The location of the hidden-platform and four visual cues on the surrounding black curtain wall are illustrated. (B) Normal retrieval in DAT+/− mice under full-cue conditions were confirmed by the measurement of platform occupancy. (C) The measurement of platform crossings further shows that both types of mice crossed the phantom platform location more significantly than the similar locations in other quadrants. (D) Impairment of memory recall in DAT+/− mice under partial cue conditions as indicated by lack of preference to the target quadrant on P2 trial. (E) Impaired pattern completion in DAT+/− mice as indicated by chance level in platform occupancy. (F) Impaired pattern completion in DAT+/− mice as indicated by chance level in platform crossings. T: Target quadrant, L: Left quadrant; O: Opposite quadrant; R: Right quadrant. Either** or *Indicates a significant between-group difference for a given time-point or probe test (**p<0.01, *p<0.05). Either ★★or ★Indicates a significant within-group difference for a given probe test (★★p<0.01, ★p<0.05).