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. Author manuscript; available in PMC: 2011 Sep 24.
Published in final edited form as: FEBS Lett. 2010 Sep 4;584(18):4121–4127. doi: 10.1016/j.febslet.2010.08.042

Figure 2. Inactivation of PHIP1 impairs postnatal whole body growth.

Figure 2

(A) Representative images of Phip+/+ (bottom) and Phip-/- (top) mice at 4 weeks of age. (B) Postnatal body weight gain profiles of Phip+/+, Phip+/- and Phip-/- mice. N = 10 per genotype, *, p < 0.05, **, p < 0.01 Phip-/- versus Phip+/+ mice. (C-D) H&E staining of hindlimb skeletal muscle cross sections from Phip+/+ (C) and Phip-/- (D) mice. (F-G) H&E staining of liver sections from Phip+/+ (F) and Phip-/- (G) mice. (I-J) H&E staining of lung sections from Phip+/+ (I) and Phip-/- (J) mice. (E, H and K) Quantification of sizes of myocytes (E), hepatocytes (H) and lung airways from Phip+/+ and Phip-/- mice. N = 3 per genotype, **, p < 0.01 Phip-/- versus Phip+/+ mice. All data are expressed as mean ± standard deviation. Scale bar: 50 μM.