Table 1.
Body weight (g) | Adipose (%) | Heart (%) | Liver (%) | Lung (%) | Hindlimb muscle (%) | Pancreas (%) | Spleen (%) | |
---|---|---|---|---|---|---|---|---|
Phip+/+ | 14.8 ± 0.73 | 1.79 ± 0.26 | 0.52 ± 0.05 | 3.72 ± 0.39 | 1.94 ± 0.19 | 1.32 ± 0.30 | 1.02 ± 0.07 | 0.40 ± 0.05 |
Phip -/- | 8.9 ± 1.63 | **0.25 ± 0.14 | 0.51 ± 0.19 | 4.18 ± 0.32 | 2.38 ± 0.42 | 0.81 ± 0.19 | 1.34 ± 0.29 | 0.32 ± 0.10 |
Phip+/+ (n = 4) and Phip-/- (n = 3) mice were sacrificed at three weeks of age. The major visceral organs, abdominal fat and hindlimb skeletal muscle were weighed and averaged according genotype. The averaged organ weight was used to calculate an organ to body weight ratio. The data are expressed as mean ± standard deviation. Note that mutant mice had a significantly lower abdominal fat content than wild-type mice.