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. 2010 Jun 21;38(19):6490–6501. doi: 10.1093/nar/gkq552

Figure 2.

Figure 2.

Overexpression of sml1-4SA, but not SML1, slows S phase progression in wild-type cells. (A) Wild-type and sml1-4SA strains were analyzed for cell-cycle progression. There is no significant difference in the duration of S phase between the two strains when the proteins are expressed endogenously (black lines to the right of the panels). (B) Overexpression of sml1-4SA (W3332-5C), but not SML1 (W2056-8A), driven by a strong galactose promoter slows S phase progression in wild-type cells. Black lines to the right of the panels indicate S-phase.