Fig. 6.

Summary of the effects of H127MO and altGPR84 mRNA injections on eye development. Shading represented in the key denotes categories of normal, minor and severe eye defect phenotypes (defined in the text). A: Uninjected embryos and control morpholino (CONMO) injected embryos typically exhibit normal development. B: Embryos injected with lissamine-tagged H127MO, show dose dependent phenotypes. Increasing severity of eye defects are seen with an increase in the amount of H127MO injected. C: Embryos co-injected with H127MO and altGPR84 mRNA exhibit a rescue phenotype with reduction in eye defects. D: Embryos injected with up to 1200pg altGPR84 mRNA alone typically exhibit normal development. Error bars indicate standard error.