Table 5.
Functioning and Well-Being Levels in Patients with One, Two or Three Anxiety Disorders
| Mental Health SF-12Composite (+) | Physical Health SF-12Composite (+) | Sheehan Disability Index (−) | Days of Activity Limitation (−) | EuroQol EQ-5D (+) | |
|---|---|---|---|---|---|
| Mean (SE) | Mean (SE) | Mean (SE) | Mean (SE) | Mean (SE) | |
| One Anxiety Disorder | |||||
| PD (N=100) | 35.7(0.9)a | 48.6(1.0)c | 14.0(0.7)d | 9.9(.9)f | 0.709(.018) |
| GAD (N=256) | 34.0(0.6)b | 51.0(0.6) | 14.8(0.4)e | 8.6(.5)g,h | 0.713(.011) |
| SAD (N=51) | 31.2(1.2) | 51.4(1.4) | 17.4(1.0) | 12.7(1.2) | 0.692(.024) |
| PTSD (N=14) | 34.4(2.4) | 50.2(2.6) | 14.8(1.9) | 14.9(2.3) | 0.658(.045) |
| Two Anxiety Disorders | |||||
| PD+GAD (N=143) | 30.8(0.7) | 49.1(0.8) | 16.8(0.5) | 10.4(.8)m | 0.644(.016) |
| PD+SAD (N=40) | 29.8(1.4) | 46.7(1.5) | 20.5(1.0)l | 14.5(1.5) | 0.605(.031) |
| PD+PTSD (N=17) | 30.4(2.1) | 44.6(2.4) | 18.1(1.6) | 16.3(2.3) | 0.618(.047) |
| GAD+SAD (N=137) | 31.2(0.7) | 51.3(0.8)j | 17.8(0.5) | 10.1(.8)m | 0.705(.016)n |
| GAD+PTSD (N=38) | 34.8(1.4)i | 46.8 (1.6)k | 16.1(1.0) | 12.4(1.5) | 0.694(.031)o |
| SAD+PTSD (N=12) | 33.4(2.4) | 47.5(2.8) | 16.4(1.8) | 16.4(2.7) | 0.668(.056) |
| Three Anxiety Disorders | |||||
| PD+GAD+SAD (N=96) | 28.1(1.0) | 48.9(1.1)p | 19.7 | 13.4(1.0) | 0.598(.01) |
| PD+GAD+PTSD (N=31) | 29.7(1.7) | 44.2(2.0) | 18.4 | 15.9(1.8) | 0.581(.035) |
| PD+SAD+PTSD (N=14) | 25.8(2.8) | 43.3(3.2) | 24q | 18.3(2.9) | 0.588(.057) |
| GAD+SAD+PTSD (N=21) | 27.1(2.1) | 45.5(2.4) | 21.5 | 15.7(2.2) | 0.558(.042) |
Note: Analyses controlled for age, gender, education, ethnicity, number of self-report chronic medical conditions, comorbid depression and study site.
Significantly different p=.0035 from SAD
Significantly different p=.0481 from SAD
Significantly different p=.0483 from GAD
Significantly different p=.006 from SAD
Significantly different p=.0203 from SAD
Significantly different p=.0419 from PTSD
Significantly different p=.0068 from PTSD
Significantly different p=.0027 from SAD
Significantly higher than all other combinations except for SAD+PTSD and PD+PTSD
Significantly higher than PD+SAD and PD+PTSD
Significantly lower than GAD+SAD
Significantly higher than all combinations except for PD+PTSD
Significantly lower than PD+SAD, PD+PTSD, and SAD+PTSD
Significantly higher than PD+GAD and PD+SAD
Significantly higher than PD+SAD
Significantly higher than PD+GAD+PTSD (p=.0433)
Significantly higher than PD+GAD+SAD (p=.0347) and PD+GAD+PTSD (p=.0143)