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. Author manuscript; available in PMC: 2011 Oct 1.
Published in final edited form as: Lancet Neurol. 2010 Oct;9(10):978–985. doi: 10.1016/S1474-4422(10)70184-8

Figure 2.

Figure 2

Graphical representation of p-values from genome-wide association study of (A) 93 familial ALS cases and 497 Finnish controls, and (B) 312 sporadic ALS cases and 497 Finnish controls. P-values are log transformed (y-axis) and plotted against chromosomes (x-axis). The red dotted line indicates the Bonferroni threshold. Signals indicated in red are on chromosome 9p21 and chromosome 21q22 and surpass the Bonferroni threshold for genome-wide significance.