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Types of discrepancies between biomarker profiles and clinical diagnoses
| Biomarker pattern | n | CDR | AD8 | Clinical diagnosis |
|---|---|---|---|---|
| Low CSF Aβ42, high PiB | 4 | 0 | 0–1 | No dementia |
| Low CSF Aβ42, normal PiB | 1 | 0 | 2 | No dementia |
| Low CSF Aβ42, normal PiB | 1 | 0.5 | 0 | Uncertain dementia |
| High CSF Aβ42, normal PiB | 1 | 0 | 2 | No dementia |
| High CSF Aβ42, normal PiB | 1 | 0.5 | 5 | Dementia |
