Table 5.
Receiver operator characteristic analyses for dementia rating measures
| Dementia rating | PiB (>0.18 = positive test) |
CSF Aβ42 (<500 pg/ml = positive test) |
||
|---|---|---|---|---|
| Area under curve (95% CI) | P-value | Area under curve (95% CI) | P-value | |
| AD8 | 0.737 (0.64–0.83) | <0.001 | 0.685 (0.60–0.77) | <0.001 |
| CDR | 0.729 (0.64–0.82) | <0.001 | 0.689 (0.60–0.77) | <0.001 |
| MMSE | 0.683 (0.58–0.78) | <0.001 | 0.630 (0.54–0.72) | 0.008 |
| SBT | 0.729 (0.64–0.82) | <0.001 | 0.596 (0.50–0.69) | 0.05 |
SBT = Short Blessed Test. Area under curve represents discrimination between positive and negative screening tests for each biomarker; P-value represents strength of association.