Table 2.
All Newly Diagnosed RA Patients | Biologic Users among RA Patients | |||
---|---|---|---|---|
Patients Who Never Initiated Biologic Therapy | Patients Who Initiated Biologic Therapy | Patients Who Do Not Continue Biologic Use Every Year Post Initiation | Patients Who Continue Biologic Use Every Year Post Initiation | |
Mean (SD) | Mean (SD) | Mean (SD) | Mean (SD) | |
Demographics | ||||
Age | 64 (15) | 59 (13) | 62(14) | 59 (13) |
Age 65 or older (%) | 50 | 33 | 47 | 35 |
Male (%) | 30 | 32 | 22 | 26 |
Socioeconomic status | ||||
Currently working (%) | 27 | 36 | 23 | 32 |
Median HH income (U.S.$) | 42,505 (10,051) | 43,132 (10,491) | 41,758 (9,852) | 42,260 (9,982) |
Urban residence (%) | 99 | 99 | 99 | 99 |
Household composition | ||||
One or more family members (in plan) (%) | 65 | 75 | 66 | 71 |
Family size | 1.91 (0.96) | 2.09 (0.98) | 1.89 (0.90) | 2.01 (0.95) |
Family size given at least one additional family member | 2.4 (0.85) | 2.46 (0.86) | 2.36 (0.78) | 2.42 (0.83) |
Comorbid conditions (RA patient) (%) | ||||
Asthma | 5 | 4 | 7 | 4 |
Hypertension | 34 | 23 | 26 | 22 |
Diabetes | 12 | 8 | 11 | 9 |
Hyperlipidemia | 12 | 8 | 6 | 7 |
Heart disease | 20 | 12 | 18 | 13 |
Depression | 6 | 6 | 6 | 4 |
Osteoarthritis | 23 | 15 | 21 | 13 |
Use of RA drugs (RA patient) (%) | ||||
NSAID or analgesics | 57 | 67 | 64 | 63 |
Corticosteroids | 41 | 65 | 68 | 60 |
Nonbiologic DMARDS | 24 | 71 | 66 | 64 |
Comorbid conditions (non-RA patients in the family) (%) | ||||
Asthma | 4 | 3 | 3 | 4 |
Hypertension | 25 | 20 | 22 | 19 |
Diabetes | 10 | 8 | 8 | 8 |
Hyperlipidemia | 34 | 22 | 26 | 26 |
Heart disease | 28 | 19 | 22 | 22 |
Depression | 4 | 5 | 5 | 5 |
Osteoarthritis | 8 | 5 | 8 | 6 |
OOP spending (RA patient) | ||||
Medical services | 3,291 (11,413) | 3,149 (14,894) | 3,352 (10,732) | 2,304 (11,698) |
Pharmacy | 642 (1,849) | 1,293 (2,399) | 1,084 (2,823) | 1,378 (2,741) |
RA drugs | 80 (312) | 694 (2,034) | 298 (877) | 805 (2,169) |
OOP spending (non-RA patients in the family) | ||||
Medical services | 2,207 (8,710) | 1,863 (7,391) | 1,610 (6,091) | 1,453 (6,061) |
Pharmacy | 474 (1,352) | 521 (1,566) | 423 (765) | 437 (1,115) |
Number of person-years | 17,713 | 1,629 | 1,352 | 3,257 |
DMARDS, disease-modifying antirheumatic drugs; HH, household; NSAID, nonsteroidal antiinflammatory drugs; OOP, out of pocket; RA, rheumatoid arthritis; SD, standard deviation.