. Author manuscript; available in PMC: 2010 Oct 28.

Published in final edited form as: Am J Cardiol. 1987 Mar 1;59(6):705–707. doi: 10.1016/0002-9149(87)91199-4

TABLE I.

Biochemical Characterization of Familial Hypercholesterolemia in the Proband and His Family

	Age (yr)	Plasma Cholesterol Concentration (mg/dl)					Achilles Tendon Xanthoma	% Normal Fibroblast Receptor Activity
	Age (yr)	Total	VLDL	LDL	HDL	CAD	Achilles Tendon Xanthoma	% Normal Fibroblast Receptor Activity
Proband	11	1,277	107	1,153	17	+	+	<3%
Mother	35	405	58	288	59	0	+	58%
Father	38	436	9	381	46	+	+	58%
Brother	15	374	29	280	65	0	+	ND

The ability of 200 µg of LDL protein/ml to stimulate esterification of ¹⁴C-oleate in 3 normal fibroblast cell lines was 10,915 ± 2,912 dpm/mg cell protein/hour and is defined as 100% activity.

To convert cholesterol values to millimoles per liter, multiply the value by 0.026.

CAD = coronary artery disease as Indicated by angina and a positive exercise stress response; HDL = high-density lipoprotein cholesterol; LDL = low-density lipoprotein cholesterol; ND = not determined; VLDL = very low density lipoprotein cholesterol.