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ER Stress–Induced Cell Death (Apoptosis) in Plants.
ER stress activates the expression of NRPs, which induces the caspase-3–like activity to trigger cell death. ER stress promotes the formation of Gαβ heterodimer to induce PCD, presumably by activating PLC or IP3 receptor pathways. Negative regulators, such as BAGs and BI-1, repress PCD in plants. Note that the counterparts of mammalian BAX or BCL-2 have not been identified in plants so far.
