Table 2. Comparison of the major tear protein components from allergic conjunctivitis patients and normal controls.
Band number | Protein name | Normal controls (n=12, in mg/ml) | Allergic conjunctivitis patients (n=21,in mg/ml) | p-value |
---|---|---|---|---|
1 |
spectrin alpha chain, brain isoform 1 |
0.20±0.06 (2.19%) |
0.20±0.06(1.67%) |
0.843 |
2 |
Serum albumin precursor |
0.17±0.05(1.93%) |
0.22±0.12(1.75%) |
0.095 |
3 |
Lactoferrin |
1.77±0.47(18.18%) |
1.96±0.28(15.96%) |
0.219 |
4 |
Serum albumin |
0.66±0.46(6.66%) |
1.43±0.82(10.73%) |
0.005* |
5 |
Ig alpha-2 chain C region |
0.90±0.48(8.76%) |
1.07±0.45(8.29%) |
0.324 |
6 |
Ig gamma-2 heavy chain C-region |
0.23±0.10(2.52%) |
0.45±0.27(3.36%) |
0.003* |
7 |
alpha-enolase |
0.15±0.05(1.55%) |
0.19±0.08(1.52%) |
0.090 |
8 |
actin, beta |
0.25±0.07(2.63%) |
0.30±0.10(2.42%) |
0.149 |
9 |
leukocyte elastase inhibitor |
0.13±0.04(1.37%) |
0.20±0.09(1.55%) |
0.003* |
10 |
annexin A1 |
0.15±0.04(1.63%) |
0.18±0.10(1.40%) |
0.235 |
11 |
Ig kappa chain C region |
0.82±0.40(8.10%) |
1.18±0.59(9.01%) |
0.067 |
12 |
- |
0.67±0.40(6.46%) |
0.89±0.27(7.19%) |
0.064 |
13 |
Lipocalin-1 precursor |
1.52±0.65(15.62%) |
1.83±0.44(14.96%) |
0.118 |
14 |
Lipocalin-1 precursor |
0.33±0.16(3.34%) |
0.42±0.12(3.35%) |
0.089 |
15 |
Lysozyme precursor |
1.72±0.40(17.87%) |
1.90±0.29(15.59%) |
0.151 |
Other Bands |
|
0.11±0.08(1.26%) |
0.17±0.18(1.23%) |
- |
SUM** | 9.80±2.67 | 12.60±2.93 | 0.010# |
Values are presented as mean ±standard deviation (%). The asterisk indicfates that the percentages were determined by: Tear protein band quantities/SUM*100%. The double asterisk indicates the SUM (the total tear protein concentration) was the sum of individual bands. The sharp (hash mark) indicates that p-values were determined by independent sample t-test. A p<0.05 was considered significant.