Table 1.

Recommended Acquisition Protocol for perfusion-weighted MR imaging (PWI).

Sequence:	Single-shot gradient-echo echoplanar imaging
Image acquisition parameters	TR ≤ 1500 ms TE = 35 to 45 ms at 1.5T TE = 25 to 30 ms at 3T Flip angle = 60° to 90° at 1.5T Flip angle = 60° at 3T
Image acquisition duration	90 to 120 seconds Image acquisition started 10 seconds before initiation of bolus injection to achieve at least 10 baseline images
Coverage and slice thickness	Field of view ≈ 24 cm Whole brain coverage using ≥ 12 slices Gap 0 to 1 mm Slice thickness 5 mm Matrix size 128 × 128
Slice orientation	Parallel to hard palate
Contrast material	Standard Gadolinium-based contrast material
Contrast volume	Single dose (for half molar agent ≈ 20 mL for 100 kg person) followed by 20 to 40 mL saline flush
Injection rate	4 to 6 mL per second. Same rate for saline
IV access	18 to 20 gauge IV line. Right antecubital vein preferred