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CypB knockdown results in the decreased PRL-induced soft agar growth and cell motility. Cells were grown on soft agar for 2 weeks, and the pictures were taken under phase contrast microscopy. (A) si-Luc without PRL treatment, (B) si-Luc with PRL treatment (200 ng/ml), (C) si-CypB without PRL treatment, (D) si-CypB with PRL treatment (200 ng/ml), (E) colony number on the soft agar, and (F) the total colony area on the soft agar. **P<0.01; ***P<0.001.
