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. 2010 Oct 28;5(10):e13727. doi: 10.1371/journal.pone.0013727

Table 3. Protective efficacies against heterologous challenge following drug treatment and 3 homologous re-infectionsa.

Group Parasite used for drug treatment and re-infection Parasite used for heterologous challenge No. of protected mice/total no. (%)
EXP6
G1 Pbb Py 10/10 (100)
G2 Pyc Pb 0/10 (0)
G3 NTd Pb 0/5 (0)
G4 NT Py 0/5 (0)
a

P. berghei- or P. yoelii-infected BALB/c mice were treated with Artemether®. The drug-cured mice were re-infected three times with homologous parasites at 4-week intervals. All mice survived these re-infections. The self-cured mice were then challenged with heterologous parasites.

b

Pb, P. berghei ANKA.

c

Py, P. yoelii 17XL.

d

NT, neither drug-treatment nor infection.