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. 2010 Oct 18;5:86. doi: 10.1186/1749-8090-5-86

Figure 1.

Figure 1

C1 INH action in plasma cascades. Depletion of C1 INH due to plasma cascade activation allows bradykinin overproduction in patients with hereditary angioedema. Bradykinin mediates acute swelling in these patients. Reproduced with permission from Weis[15].