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Control compounds designed by removing the functionality from the 4-postion (14b) or by methylating the oxalamide (15a–c). Control compounds are >30-fold less potent than their parent compound (listed below the compound in parenthesis) when tested against hGX (14b and 15a), human and mouse GIIA, GV, and GX (15b), or human GIIA (15c).
