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. Author manuscript; available in PMC: 2010 Oct 28.
Published in final edited form as: J Med Chem. 2008 Jul 8;51(15):4708–4714. doi: 10.1021/jm800422v

Table 2.

IC50 Values of 11d Derivatives against hGX sPLA2a

graphic file with name nihms241734t12.jpg
hGX
Comp R IC50 (nM)
13a graphic file with name nihms241734t13.jpg 80±10
13b graphic file with name nihms241734t14.jpg 540±60
13c graphic file with name nihms241734t15.jpg 140±30
13d graphic file with name nihms241734t16.jpg 14±3
13e graphic file with name nihms241734t17.jpg 320±30
13f graphic file with name nihms241734t18.jpg 11±1
13g graphic file with name nihms241734t19.jpg 70±20
13h graphic file with name nihms241734t20.jpg 7±2
13i graphic file with name nihms241734t21.jpg 30±10
a

IC50 values are reported as the mean of duplicate or triplicate analysis with standard deviations.